PT-141 stimulates the brain's melanocortin receptors. This causes the brain to release nitric oxide, which increases blood flow to the sex organs. PT-141 also targets the nervous system to enhance sexual arousal and performance.

PT-141 is approved by the FDA for hypoactive sexual desire disorder in premenopausal women.

It can also be beneficial for women experiencing stress-related decreases in libido or hormonal changes due to perimenopause or menopause.